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Testing the Effectiveness of Ethanol Extract from Pandan Laeves (Pandanus amarylifolius Roxb) As a Healer of Incision Wounds in White Rats (Rattus norvegicus)

Priska C. LondoranProgram Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon.Jabes W. KanterProgram Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon.Christel N. SambouProgram Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon.Hariyadi HariyadiProgram Studi Farmasi, Fakultas MIPA, Universitas Kristen Indonesia Tomohon.
Journal Pharmaceutical And Sciences (Sinta 3)No. 1 (2025)12 Juli 2023hal. 974-979
DOI10.36490/journal-jps.com.v6i3.174

Abstrak

An incision is a wound that splits the skin area due to being cut by a sharp object. Indonesian people use medicinal plants very much in traditional or modern medicine. One of the plants that can be used as a medicinal ingredient is fragrant pandan leaves which can accelerate the wound healing process. This study aims to determine the level of effectiveness of pandan leaf extract as a healer for cuts. This study used 15 white rats which were then slashed on their backs using a 1 cm long scalpel with a depth of ± 2 mm. This study used a laboratory experiment using a completely randomized design consisting of 5 treatment groups, including 1 negative control, positive control (10 percent povidone iodine) and 3 graded concentrations, namely pandan leaf extract concentrations of 5.10 to 15 percent with 2 each. repetition times. The results of measuring the length of the wound in rats showed that fragrant pandan leaf extract with a concentration of 10 percent and 15 percent had the same effectiveness.

Kata Kunci

Effectivenesscut woundspandan leaf extractwhite ratsEffectivenesscut woundspandan leaf extractwhite rats

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Testing the Effectiveness of Ethanol Extract from Pandan Laeves (Pandanus amarylifolius Roxb) As a Healer of Incision Wounds in White Rats (Rattus norvegicus) | Journal Pharmaceutical And Sciences | Publiora