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A Comparative Study on Antioxidant Activity of Infusion and Decoction of (Cayratia trifolia (L.) Domin)

Angel MangiwaSekolah Tinggi Ilmu Farmasi Makassar, Makassar, Sulawesi Selatan, Indonesia.Mirna MaulidahSekolah Tinggi Ilmu Farmasi Makassar, Makassar, Sulawesi Selatan, Indonesia.Tipalmaton R PatulenSekolah Tinggi Ilmu Farmasi Makassar, Makassar, Sulawesi Selatan, Indonesia.Dhea K KendeSekolah Tinggi Ilmu Farmasi Makassar, Makassar, Sulawesi Selatan, Indonesia.Ismail IsmailSekolah Tinggi Ilmu Farmasi Makassar, Makassar, Sulawesi Selatan, Indonesia.Desy A LestariSekolah Tinggi Ilmu Farmasi Makassar, Makassar, Sulawesi Selatan, Indonesia.Maulita IndrisariSekolah Tinggi Ilmu Farmasi Makassar, Makassar, Sulawesi Selatan, Indonesia.Lukman MusliminSekolah Tinggi Ilmu Farmasi Makassar, Makassar, Sulawesi Selatan, Indonesia.
Journal Pharmaceutical And Sciences (Sinta 3)No. 1 (2025)11 Juli 2023hal. 909-915
DOI10.36490/journal-jps.com.v6i3.55

Abstrak

The number of patients with neurodegenerative disorders increased, especially in the productive age. The neurodegenerative disorder can be prevented by synthetic and natural antioxidants such as from plants. The herb of galling, Cayratia trifolia (L.) Domin), has long been traditionally used to prevent degenerative diseases by drinking decoction. The current study aimed to compare the antioxidant capability between infusion and decoction of galling against DPPH. The herbs were extracted with two methods, namely infusion, and decoction. This study used 7 different serial concentrations ranging 7.81 till 500 µg/mL, while the optical density was recorded at 515 nm using a spectrophotometer. The results demostrated that both infusion and decoction have antioxidant activity against DPPH with IC50 values of 87.55±1.01 (strong category) and 65.38±2.26 µg/mL (strong category), respectively. There was a statistically significant (p<0.05) between the IC50 values of infusion and decoction. In conclusion, galling is efficacious as an antioxidant source for preventing and treating degenerative diseases.

Kata Kunci

AntioxidantCayratia trifolia (L.) DominDecoctionInfusionDPPHAntioxidantCayratia trifolia (L.) DominDecoctionInfusionDPPH

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A Comparative Study on Antioxidant Activity of Infusion and Decoction of (Cayratia trifolia (L.) Domin) | Journal Pharmaceutical And Sciences | Publiora