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Phytochemical screening and antioxidant activity of ethanolic extract of nutmeg flesh (Myristica fragrans) from southern Aceh Province, Indonesia.

Saiful Azhari Department of pharmacy, STIKes Assyifa Aceh, Aceh, Indonesia.Rina Kurniaty Department of pharmacy, STIKes Assyifa Aceh, Aceh, Indonesia.Muhammad YusufDepartment of pharmacy, STIKes Assyifa Aceh, Aceh, Indonesia.Riza Zulyani Universitas Islam Negeri Ar-Raniry, Banda Aceh, IndonesiaMahmudi Mahmudi Department of pharmacy, STIKes Assyifa Aceh, Aceh, Indonesia.Wahyu Mustika RaniDepartment of pharmacy, STIKes Assyifa Aceh, Aceh, Indonesia.Mutia Farida Department of pharmacy, STIKes Assyifa Aceh, Aceh, Indonesia.
Journal Pharmaceutical And Sciences (Sinta 3)No. 1 (2025)21 Oktober 2024hal. 537-543
DOI10.36490/journal-jps.com.v7i4.421

Abstrak

The nutmeg fruit (Myristica fragrans) shows the presence of secondary metabolite compounds and has antioxidant activity. The nutmeg examined in this study is the flesh of the fruit and dried for seven days to obtain simplisia. The extraction process is by maceration method using 96% ethanol solvent. Based on the results of phytochemical screening of ethanol extracts of nutmeg flesh showed the presence of secondary metabolite compounds, which are groups of alkaloids, steroids, saponins and flavonoids. The results of antioxidant activity of ethanol extract of nutmeg flesh have an IC50 value of 22.88 ppm. In this study using vitamin C as a positive control for comparison with the IC50 value obtained is 3.82 ppm. The more secondary metabolite compounds in an extract, the higher the antioxidant activity.

Kata Kunci

AntioxidantNutmegExtractMyristica fragransPhytochemical screeningAntioxidantNutmegExtractMyristica fragransPhytochemical screening

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Phytochemical screening and antioxidant activity of ethanolic extract of nutmeg flesh (Myristica fragrans) from southern Aceh Province, Indonesia. | Journal Pharmaceutical And Sciences | Publiora