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Evaluation of Antihypertensive Drug Use in BPJS Patient Prescriptions from Mataram City Hospital Dispensed at KF 134 Pejanggik Pharmacy and KF 458 Catur Warga Pharmacy Based on ATC/DDD and DU 90%

Yogi Mujizat Hamzani Department of Pharmacy, Faculty of Pharmacy, Setia Budi University, Surakarta City, Central Java, Indonesia Tri Murti Andayani Department of Pharmacy, Faculty of Pharmacy, Gadjah Mada University, Sleman, DI Yogyakarta, Indonesia.Lucia Vita Inandha DewiDepartment of Pharmacy, Faculty of Pharmacy, Setia Budi University, Surakarta City, Central Java, Indonesia.
Journal Pharmaceutical And Sciences (Sinta 3)No. 1 (2025)25 Agustus 2025hal. 1786-1794
DOI10.36490/journal-jps.com.v8i3.1028

Abstrak

Background: Hypertension is a persistent condition of high blood pressure (systolic >140 mmHg or diastolic >90 mmHg). As a chronic disease requiring long-term treatment, the therapy for hypertensive patients needs to be evaluated regularly. Objective: This study aimed to determine the consumption profile of antihypertensive drugs using the ATC/DDD and DU 90% methods and to assess their compliance with the National Formulary (FORNAS). Methods: This research used a cross-sectional design with retrospective data collection. The samples were prescriptions for BPJS hypertension patients from Mataram City Hospital for the period of January-December 2024, redeemed at KF 134 Pejanggik Pharmacy and KF 458 Catur Warga Pharmacy. The data were analyzed using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) and Drug Utilization 90% (DU 90%) methods. Results: The results showed that the most consumed antihypertensive class was ARBs, specifically candesartan, with a value of 13,082.25 DDD/1000 PPD at KF 134 Pejanggik and 7,215.33 DDD/1000 PPD at KF 458 Catur Warga. The drugs included in the DU 90% segment were candesartan, ramipril, amlodipine, and bisoprolol at both pharmacies, with the addition of valsartan at KF 134 Pejanggik. Compliance with drug use guidelines for FORNAS was 92% at KF 134 Pejanggik Pharmacy and 90% at KF 458 Catur Warga Pharmacy. Conclusion: The use of antihypertensive drugs in both pharmacies is in accordance with FORNAS, with high compliance percentages, indicating rational drug prescribing practices.

Kata Kunci

AntihypertensivesATC/DDDDU 90%CandesartanPharmaciesAntihypertensivesATC/DDDDU 90%CandesartanPharmacies

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Evaluation of Antihypertensive Drug Use in BPJS Patient Prescriptions from Mataram City Hospital Dispensed at KF 134 Pejanggik Pharmacy and KF 458 Catur Warga Pharmacy Based on ATC/DDD and DU 90% | Journal Pharmaceutical And Sciences | Publiora