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Autologous Parietal Peritoneum as a Biliary Interposition Conduit for Complex Post-Cholecystectomy Bile Duct Injuries: A Feasibility Study and Report of Two Cases

Elena WandantyasAnung Noto Nugroho
Bioscientia Medicina : Journal of Biomedicine and Translational Research (Sinta 3)Vol. 0 No. 015 September 2025
DOI10.37275/bsm.v9i12.1448

Abstrak

Background: Complex iatrogenic bile duct injuries (BDIs) are formidable surgical challenges, with Roux-en-Y hepaticojejunostomy (RYHJ) being the standard reconstruction. However, RYHJ permanently alters gastrointestinal physiology and is associated with significant long-term morbidity. This has prompted a search for physiology-preserving alternatives. We describe a novel technique using a tubularized autologous parietal peritoneal graft for biliary reconstruction. Case presentation: This report details the successful management of two patients with high-grade, post-cholecystectomy BDIs (Strasberg-Bismuth Type E1 and E3). Both patients presented with obstructive jaundice and controlled biliary fistulae. Definitive single-stage reconstruction was performed. A segment of parietal peritoneum was harvested, tubularized over a T-tube to create an interposition conduit, and anastomosed to bridge the biliary defect. The repair was reinforced with a pedicled omental flap. Both patients demonstrated complete resolution of jaundice and normalization of liver function tests, with radiological evidence of graft patency and no stricture at 12-month follow-up. Conclusion: This preliminary experience in two patients suggests that the use of a tubularized autologous parietal peritoneal graft is a surgically feasible technique for the reconstruction of complex BDIs. This approach offers a potential physiology-preserving alternative to traditional bilioenteric anastomosis. Its safety, efficacy, and long-term durability remain unknown and require rigorous evaluation in larger prospective studies.

Kata Kunci

Autologous graftBile duct injuryBiliary reconstructionCholecystectomyPeritoneal conduit

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Autologous Parietal Peritoneum as a Biliary Interposition Conduit for Complex Post-Cholecystectomy Bile Duct Injuries: A Feasibility Study and Report of Two Cases | Bioscientia Medicina : Journal of Biomedicine and Translational Research | Publiora